|
TMPJ-00486
|
SUMO2 Protein, Human, Recombinant (His)
HSMT3,Ubiquitin-Like Protein SMT3A,SUMO-3,SMT3A,Sen...
|
Human
|
E. coli
|
|
Small Ubiquitin-Related Modifier 2 (SUMO2) is an Ubiquitin-like protein that belongs to the ubiquitin family with SUMO subfamily. It is a family of small, related proteins that can be enzymatically attached to a target protein by a post-translational modification process termed sumoylation. SUMO2 can be covalently attached to proteins as a monomer or as a lysine-linked polymer. Covalent attachment via an isopeptidebond to its substrates requires prior activation by the E1 complex SAE1-SAE2 and l... |
|
TMPJ-01021
|
SUMO3 Protein, Human, Recombinant
SMT3H1,SMT3 Homolog 1,SUMO3,Small Ubiquitin-Related...
|
Human
|
E. coli
|
|
SUMO3 Protein, Human, Recombinant is expressed in E. coli expression system. The predicted molecular weight is 18 KDa and the accession number is P55854. |
|
TMPJ-01023
|
SUMO3 Protein, Human, Recombinant (E.coli, His)
Ubiquitin-Like Protein SMT3B,SMT3H1,SUMO-3,Small Ub...
|
Human
|
E. coli
|
|
SUMO3 Protein, Human, Recombinant (E.coli, His) is expressed in E. coli expression system with N-6xHis tag. The predicted molecular weight is 19 KDa and the accession number is P55854. |
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TMPJ-01022
|
SUMO3 Protein, Human, Recombinant (HEK293, His)
SMT3 homolog 1,Smt3A,Small ubiquitin-related modifier 3,Ubiq...
|
Human
|
HEK293 Cells
|
|
Small ubiquitin-like modifier (SUMO), also known as SUMO homologue and SMT3, is a member of the superfamily of ubiquitin-like polypeptides that become covalently attached to various intracellular target proteins as a way to alter their function, location, and/or half-life. Small ubiquitin-like modifiers include SUMO1, SUMO2, SUMO3, and SUMO4. Except for SUMO4, all other SUMOs are ubiquitously expressed, including in the brain. In human, SUMO2 and SUMO3 are two highly homologous proteins, collect... |
|
TMPJ-01295
|
SENP7 Protein, Human, Recombinant
SSP2,KIAA1707,Sentrin-Specific Protease 7,SUSP2...
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Human
|
E. coli
|
|
Sentrin-Specific Protease 7 (SENP7) acts as a SUMO-2/3-specific protease. SENP7 is likely to regulate the metabolism of poly-SUMO-2/3 rather than SUMO-1 conjugation in vivo. SENP7 has a restricted substrate specificity, and displaying paralogue-specific isopeptidase activity. The C-terminal catalytic domain of SENP7 depolymerized poly-SUMO-2 chains but does not have activity against poly-SUMO-1 chains. SENP7 also had isopeptidase activity against di-SUMO-2- and SUMO-2-modified RanGAP1 (Ran GTPas... |
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TMPJ-01336
|
SENP2 Protein, Human, Recombinant
Sentrin/SUMO-specific protease SENP2,Axam<...
|
Human
|
E. coli
|
|
SENP2 is an enzyme that belongs to the peptidase C48 family. SENP2 is a protease that catalyzes two essential functions in the SUMO pathway: processing of full-length SUMO1, SUMO2 and SUMO3 to their mature forms and deconjugation of SUMO1, SUMO2 and SUMO3 from targeted proteins. SUMO1 is a small ubiquitin-like protein that can be covalently conjugated to other proteins. It has been implicated as a down-regulator of CTNNB1 levels and may therefore be a modulator of the Wnt pathway. |
|
TMPJ-01278
|
SENP8 Protein, Human, Recombinant (His)
DEN1,Protease Cysteine 2,NEDP1,Sentrin-Specific Pro...
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Human
|
E. coli
|
|
Sentrin-Specific Protease 8 (SENP8) mediates the reversible covalent modification of proteins by NEDD8. SENP8 catalyzes the full-length NEDD8 to generate its mature form and deconjugation of NEDD8 from targeted proteins such as CUL2 , CUL4A in vivo, or p53. but it does not show activity against ubiquitin or SUMO proteins. |
|
TMPY-01887
|
MCP-2 Protein, Human, Recombinant (SUMO)
HC14,MCP-2,chemokine (C-C motif) ligand 8,SCYA10,MC...
|
Human
|
E. coli
|
|
MCP-2 Protein, Human, Recombinant (SUMO) is expressed in E. coli expression system with SUMO tag. The predicted molecular weight is 21.7 kDa and the accession number is P80075-1. |
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TMPH-01872
|
Plastin-2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Actin-binding protein. Plays a role in the activation of T-cells in response to costimulation through TCR/CD3 and CD2 or CD28. Modulates the cell surface expression of IL2RA/CD25 and CD69. Plastin-2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 86.2 kDa and the accession number is P13796. |
|
TMPH-02526
|
Arginase-2/ARG2 Protein, Mouse, Recombinant (His & SUMO)
Arginase II,Kidney-type arginase,Type II arginase,Arg2
|
Mouse
|
E. coli
|
|
May play a role in the regulation of extra-urea cycle arginine metabolism and also in down-regulation of nitric oxide synthesis. Extrahepatic arginase functions to regulate L-arginine bioavailability to nitric oxid synthase (NOS). Arginine metabolism is a critical regulator of innate and adaptive immune responses. Seems to be involved in negative regulation of the survival capacity of activated CD4(+) and CD8(+) T cells. May suppress inflammation-related signaling in asthmatic airway epithelium.... |
|
TMPH-01032
|
Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO)
Calponin-2,Calponin H2, smooth muscle,Neut...
|
Human
|
E. coli
|
|
Thin filament-associated protein that is implicated in the regulation and modulation of smooth muscle contraction. It is capable of binding to actin, calmodulin and tropomyosin. The interaction of calponin with actin inhibits the actomyosin Mg-ATPase activity. Calponin-2/CNN2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.6 kDa and the accession number is Q99439. |
|
TMPH-02304
|
Vasohibin-2/VASH2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Tyrosine carboxypeptidase that removes the C-terminal tyrosine residue of alpha-tubulin, thereby regulating microtubule dynamics and function. Critical for spindle function and accurate chromosome segregation during mitosis since microtuble detyronisation regulates mitotic spindle length and postioning. Acts as an activator of angiogenesis: expressed in infiltrating mononuclear cells in the sprouting front to promote angiogenesis. Plays a role in axon formation. Vasohibin-2/VASH2 Protein, Human,... |
|
TMPH-00771
|
Ferritin-2 Protein, Glycine max, Recombinant (His & SUMO)
|
Glycine max
|
E. coli
|
|
Stores iron in a soluble, non-toxic, readily available form. Important for iron homeostasis. Has ferroxidase activity. Iron is taken up in the ferrous form and deposited as ferric hydroxides after oxidation. |
|
TMPH-00126
|
Aspergillopepsin-2 Protein, Aspergillus niger, Recombinant (His & SUMO)
Aspergillopepsin-2,Acid protease A,Aspergillopepsin...
|
Aspergillus niger
|
E. coli
|
|
N/A. Aspergillopepsin-2 Protein, Aspergillus niger, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 19.9 kDa and the accession number is P24665. |
|
TMPH-00080
|
Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO)
Catalase-2,CAT,CAT2
|
Arabidopsis thaliana
|
E. coli
|
|
Occurs in almost all aerobically respiring organisms and serves to protect cells from the toxic effects of hydrogen peroxide. Catalase-2 Protein, Arabidopsis thaliana, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.9 kDa and the accession number is P25819. |
|
TMPH-02442
|
IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO)
|
Rhesus
|
E. coli
|
|
Produced by T-cells in response to antigenic or mitogenic stimulation, this protein is required for T-cell proliferation and other activities crucial to regulation of the immune response. Can stimulate B-cells, monocytes, lymphokine-activated killer cells, natural killer cells, and glioma cells. IL-2 Protein, Rhesus macaque, Recombinant (His & Myc & SUMO) is expressed in E. coli expression system with N-10xHis-SUMO and C-Myc tag. The predicted molecular weight is 35.5 kDa and the accession numbe... |
|
TMPH-03541
|
Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO)
Enterotoxin type C-2,SEC2,entC2
|
Staphylococcus aureus
|
E. coli
|
|
Staphylococcal enterotoxin that activates the host immune system by binding as unprocessed molecules to major histocompatibility (MHC) complex class II and T-cell receptor (TCR) molecules. In turn, this ternary complex activates a large number of T-lymphocytes initiating a systemic release of proinflammatory cytokines. Causes also the intoxication staphylococcal food poisoning syndrome. Enterotoxin type C-2 Protein, S. aureus, Recombinant (His & SUMO) is expressed in E. coli expression system wi... |
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TMPH-01320
|
CAPZA2 Protein, Human, Recombinant (His & SUMO)
CAPZA2,CapZ alpha-2,F-actin-capping protei...
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Human
|
E. coli
|
|
F-actin-capping proteins bind in a Ca(2+)-independent manner to the fast growing ends of actin filaments (barbed end) thereby blocking the exchange of subunits at these ends. Unlike other capping proteins (such as gelsolin and severin), these proteins do not sever actin filaments. CAPZA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 48.8 kDa and the accession number is P47755. |
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TMPH-02131
|
SKP2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Substrate recognition component of a SCF (SKP1-CUL1-F-box protein) E3 ubiquitin-protein ligase complex which mediates the ubiquitination and subsequent proteasomal degradation of target proteins involved in cell cycle progression, signal transduction and transcription. Specifically recognizes phosphorylated CDKN1B/p27kip and is involved in regulation of G1/S transition. Degradation of CDKN1B/p27kip also requires CKS1. Recognizes target proteins ORC1, CDT1, RBL2, KMT2A/MLL1, CDK9, RAG2, FOXO1, UB... |
|
TMPH-01737
|
PGLYRP2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
May play a scavenger role by digesting biologically active peptidoglycan (PGN) into biologically inactive fragments. Has no direct bacteriolytic activity. PGLYRP2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 76.0 kDa and the accession number is Q96PD5. |
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TMPH-02079
|
SPTLC2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Serine palmitoyltransferase (SPT). The heterodimer formed with LCB1/SPTLC1 constitutes the catalytic core. The composition of the serine palmitoyltransferase (SPT) complex determines the substrate preference. The SPTLC1-SPTLC2-SPTSSA complex shows a strong preference for C16-CoA substrate, while the SPTLC1-SPTLC2-SPTSSB complex displays a preference for C18-CoA substrate. Plays an important role in de novo sphyngolipid biosynthesis which is crucial for adipogenesis. SPTLC2 Protein, Human, Recomb... |
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TMPH-02299
|
UGP2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
UTP--glucose-1-phosphate uridylyltransferase catalyzing the conversion of glucose-1-phosphate into UDP-glucose, a crucial precursor for the production of glycogen. |
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TMPH-01508
|
HABP2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Cleaves the alpha-chain at multiple sites and the beta-chain between 'Lys-53' and 'Lys-54' but not the gamma-chain of fibrinogen and therefore does not initiate the formation of the fibrin clot and does not cause the fibrinolysis directly. It does not cleave (activate) prothrombin and plasminogen but converts the inactive single chain urinary plasminogen activator (pro-urokinase) to the active two chain form. Activates coagulation factor VII. May function as a tumor suppressor negatively regulat... |
|
TMPH-02183
|
CCT2 Protein, Human, Recombinant (His & SUMO)
CCT2,99D8.1,CCT-beta,TCP-1-beta,CCTB,T-complex prot...
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Human
|
E. coli
|
|
Component of the chaperonin-containing T-complex (TRiC), a molecular chaperone complex that assists the folding of proteins upon ATP hydrolysis. The TRiC complex mediates the folding of WRAP53/TCAB1, thereby regulating telomere maintenance. As part of the TRiC complex may play a role in the assembly of BBSome, a complex involved in ciliogenesis regulating transports vesicles to the cilia. The TRiC complex plays a role in the folding of actin and tubulin. CCT2 Protein, Human, Recombinant (His & S... |
|
TMPH-01446
|
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein B (His & SUMO)
|
HHV-2
|
E. coli
|
|
Human herpesvirus 2 (HHV-2) (strain HG52) Envelope glycoprotein B (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 44.4 kDa and the accession number is P08666. |
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TMPH-01699
|
SMAD2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Receptor-regulated SMAD (R-SMAD) that is an intracellular signal transducer and transcriptional modulator activated by TGF-beta (transforming growth factor) and activin type 1 receptor kinases. Binds the TRE element in the promoter region of many genes that are regulated by TGF-beta and, on formation of the SMAD2/SMAD4 complex, activates transcription. May act as a tumor suppressor in colorectal carcinoma. Positively regulates PDPK1 kinase activity by stimulating its dissociation from the 14-3-3... |
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TMPH-01328
|
FBXL2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
FBXL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 63.1 kDa and the accession number is Q9UKC9. |
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TMPH-01850
|
PNPLA2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
PNPLA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 71.3 kDa and the accession number is Q96AD5. |
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TMPH-02157
|
SFTA2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Putative surfactant protein. |
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TMPH-01319
|
EYA2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
EYA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 72.7 kDa and the accession number is O00167. |
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TMPH-00267
|
GJD2 Protein, Bovine, Recombinant (His & SUMO)
|
Bovine
|
E. coli
|
|
One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. GJD2 Protein, Bovine, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 49.1 kDa and the accession number is Q866T7. |
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TMPH-00960
|
NAT2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
NAT2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
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TMPH-01598
|
CCBL2 Protein, Human, Recombinant (His & SUMO)
KAT3,Kynurenine--oxoglutarate transaminase 3,CCBL2,...
|
Human
|
E. coli
|
|
CCBL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.4 kDa and the accession number is Q6YP21. |
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TMPH-02540
|
GRK2 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse
|
E. coli
|
|
Specifically phosphorylates the agonist-occupied form of the beta-adrenergic and closely related receptors, probably inducing a desensitization of them. Key regulator of LPAR1 signaling. Competes with RALA for binding to LPAR1 thus affecting the signaling properties of the receptor. Desensitizes LPAR1 and LPAR2 in a phosphorylation-independent manner. Positively regulates ciliary smoothened (SMO)-dependent Hedgehog (Hh) signaling pathway by facilitating the trafficking of SMO into the cilium and... |
|
TMPH-00889
|
FADS2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
FADS2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.9 kDa and the accession number is O95864. |
|
TMPH-00831
|
PMP2 Protein, Horse, Recombinant (His & SUMO)
|
Horse
|
E. coli
|
|
May play a role in lipid transport protein in Schwann cells. May bind cholesterol. PMP2 Protein, Horse, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 30.4 kDa and the accession number is P0C6G6. |
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TMPH-01966
|
PADI2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
PADI2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
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TMPH-02851
|
PDIA2 Protein, Mouse, Recombinant (His & SUMO)
|
Mouse
|
E. coli
|
|
Acts as an intracellular estrogen-binding protein. May be involved in modulating cellular levels and biological functions of estrogens in the pancreas. May act as a chaperone that inhibits aggregation of misfolded proteins. |
|
TMPH-01906
|
SMARCA2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
SMARCA2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
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TMPH-02021
|
RGS2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
RGS2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli. |
|
TMPH-02309
|
KCNAB2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
KCNAB2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 57.0 kDa and the accession number is Q13303. |
|
TMPH-02056
|
RUVBL2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
RUVBL2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 67.0 kDa and the accession number is Q9Y230. |
|
TMPH-02150
|
SUCLG2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. SUCLG2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system wit... |
|
TMPH-03132
|
AVPR2 Protein, Pig, Recombinant (His & SUMO)
AVPR2,Vasopressin V2 receptor,V2R...
|
Sus scrofa (Pig)
|
E. coli
|
|
Receptor for arginine vasopressin. The activity of this receptor is mediated by G proteins which activate adenylate cyclase. Involved in renal water reabsorption. AVPR2 Protein, Pig, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 24.7 kDa and the accession number is P32307. |
|
TMPH-02198
|
TXNRD2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Involved in the control of reactive oxygen species levels and the regulation of mitochondrial redox homeostasis. Maintains thioredoxin in a reduced state. May play a role in redox-regulated cell signaling. |
|
TMPH-01954
|
SSX2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Could act as a modulator of transcription. SSX2 Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 37.6 kDa and the accession number is Q16385. |
|
TMPH-01371
|
GM2A Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
GM2A Protein, Human, Recombinant (His & SUMO) is expressed in E. coli expression system with N-6xHis-SUMO tag. The predicted molecular weight is 33.6 kDa and the accession number is P17900. |
|
TMPH-01510
|
HAO2 Protein, Human, Recombinant (His & SUMO)
|
Human
|
E. coli
|
|
Catalyzes the oxidation of L-alpha-hydroxy acids as well as, more slowly, that of L-alpha-amino acids. |
|
TMPH-02268
|
AGTR2 Protein, Human, Recombinant (His & SUMO)
AT2 receptor,Angiotensin II type-2 recepto...
|
Human
|
E. coli
|
|
Receptor for angiotensin II. Cooperates with MTUS1 to inhibit ERK2 activation and cell proliferation. |
|
TMPH-00947
|
APOC2 Protein, Human, Recombinant (His & SUMO)
ApoC-II,APC2,Apolipoprotein C-II,Apolipoprotein C
|
Human
|
E. coli
|
|
Component of chylomicrons, very low-density lipoproteins (VLDL), low-density lipoproteins (LDL), and high-density lipoproteins (HDL) in plasma. Plays an important role in lipoprotein metabolism as an activator of lipoprotein lipase. Both proapolipoprotein C-II and apolipoprotein C-II can activate lipoprotein lipase. In normolipidemic individuals, it is mainly distributed in the HDL, whereas in hypertriglyceridemic individuals, predominantly found in the VLDL and LDL. APOC2 Protein, Human, Recomb... |
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